START 'EM

Colts: QB Peyton Manning, WR Reggie Wayne, WR Pierre Garcon, TE Jacob Tamme, K Adam Vinatieri.

Titans: RB Chris Johnson, K Rob Bironas.

Quick slants: Manning has been at his worst in Indy's last three games, throwing 11 interceptions. Even while struggling, though, he's thrown for 1,046 yards and eight touchdowns in that span. ... Wayne has 27 receptions for 342 yards and two TDs in his last three. ... Garcon has had five or more receptions in four consecutive games. ... Tamme has been limited by a hamstring injury, but is expected to play. If he's listed as active an hour before game time, play the tight end who has 42 receptions for 416 yards and three TDs in six games in place of Dallas Clark. ... Vinatieri and Bironas are each averaging 7.4 points per game. The latter has missed one kick all year (21-for-22 on field goals and perfect in 26 point-after attempts). ... Johnson's dreams of a record-setting season seem a faint memory after a two-game span in which he's had a combined 20 carries for 58 yards. He has 74 total yards in the two contests.

SIT 'EM

Colts: RB Joseph Addai, RB Donald Brown, RB Javarris James, RB Mike Hart, WR Austin Collie, WR Blair White, defense and special teams.

Titans: QB Kerry Collins, WR Nate Washington, WR Kenny Britt, TE Bo Scaife, defense and special teams.

Quick slants: Addai is out again with a shoulder injury, and Hart will sit with an ankle ailment. ... Brown is expected to play through an ankle injury, but he has one TD on 107 touches this season. ... James had two TDs last week and has three scores in his last four games, but he has all of 21 carries for 47 yards in the four contests. ... Collie could return after missing the last two games with a concussion, but he's a risky play against a Titans defense that has one more interception (15) than TD passes allowed (14). ... Washington had five catches for 117 yards in Week 11, but has four receptions for 50 yards and no TDs in his last two. ... Britt is expected to return after missing the Titans' last four games with a hamstring ailment. He had seven TDs in a five-game span between Weeks 3 and 7, but I wouldn't risk playing him in the first week of the fantasy playoffs. ... The Colts' defense ranks 18th overall (342.8 yards per game) and is 22nd in points allowed (24.2). Indy ranks 29th against the run (142.8 yards, 13 TDs) and fourth vs. the pass. ... The Titans' defense is 24th overall (362.1 yards per game), but is eighth in points allowed at 19.6 per contest. Tennessee is 22nd against the run (123.4 yards, six rushing TDs) and 23rd vs. the pass (239 yards, 14 TDs, 15 picks).